Molecular Docking: A Review Paper

Namrata Arya; Arminder Kaur

doi:10.55524/ijirem.2022.9.1.25

Abstract

Molecular docking basically explains about the orientation of a molecule preferred to the other molecule in a manner as in when they attach to each other in order to get a steady complex. By using scoring functions further the power of alliance or the irrevocable affinity of the different molecules is predicted by the preferred orientation of the two molecules. These interactions, which are achieved by molecular docking between important biological components such as proteins, peptides, nucleic acid, carbohydrates, and lipids, are crucial in signal transduction. Further, these interactions between two molecules which are being performed by the help of molecular docking also helps in predicting the type of signals produced. Therefore, molecular docking is helpful in predicting both strength and type of signals produced by the molecules. Because of its ability to predict the coupling compliance of small particle ligands to the appropriate target restriction site, molecular docking is among the most often used strategies in structure-based drug design. Characterization of the coupling conduct assumes a significant job in discerning structure of medications just as to clarify crucial biochemical procedures.

Keywords

Docking, Ligand, Molecular, Models, Orientation.

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Cites this article as

N. A. , A. K. , "Molecular Docking: A Review Paper", International Journal of Innovative Research in Engineering & Management (IJIREM), Vol-9, Issue-1, Page No-140-146, 2022. Available from: https://doi.org/10.55524/ijirem.2022.9.1.25